diff --git a/isso/__init__.py b/isso/__init__.py
index 2ff200f..6e8b2e4 100644
--- a/isso/__init__.py
+++ b/isso/__init__.py
@@ -33,10 +33,11 @@ dist = pkg_resources.get_distribution("isso")
 try:
     import uwsgi
 except ImportError:
+    uwsgi = None
     try:
         import gevent.monkey; gevent.monkey.patch_all()
     except ImportError:
-        pass
+        gevent = None
 
 import sys
 import os
@@ -46,6 +47,7 @@ import tempfile
 
 from os.path import dirname, join
 from argparse import ArgumentParser
+from functools import partial, reduce
 
 from itsdangerous import URLSafeTimedSerializer
 
@@ -56,12 +58,13 @@ from werkzeug.wsgi import SharedDataMiddleware
 from werkzeug.local import Local, LocalManager
 from werkzeug.serving import run_simple
 from werkzeug.contrib.fixers import ProxyFix
+from werkzeug.contrib.profiler import ProfilerMiddleware
 
 local = Local()
 local_manager = LocalManager([local])
 
 from isso import db, migrate, wsgi, ext, views
-from isso.core import ThreadedMixin, uWSGIMixin, Config
+from isso.core import ThreadedMixin, ProcessMixin, uWSGIMixin, Config
 from isso.utils import parse, http, JSONRequest, origin
 from isso.views import comments
 
@@ -139,13 +142,14 @@ class Isso(object):
 
 def make_app(conf=None):
 
-    try:
-        import uwsgi
-    except ImportError:
+    if uwsgi:
+        class App(Isso, uWSGIMixin):
+            pass
+    elif gevent or sys.argv[0].endswith("isso"):
         class App(Isso, ThreadedMixin):
             pass
     else:
-        class App(Isso, uWSGIMixin):
+        class App(Isso, ProcessMixin):
             pass
 
     isso = App(conf)
@@ -158,23 +162,22 @@ def make_app(conf=None):
     else:
         logger.warn("unable to connect to HTTP server")
 
+    wrapper = [local_manager.make_middleware]
+
     if isso.conf.getboolean("server", "profile"):
-        from werkzeug.contrib.profiler import ProfilerMiddleware as Profiler
-        ProfilerMiddleware = lambda app: Profiler(app, sort_by=("cumtime", ), restrictions=("isso/(?!lib)", 10))
-    else:
-        ProfilerMiddleware = lambda app: app
+        wrapper.append(partial(ProfilerMiddleware,
+            sort_by=("cumtime", ), restrictions=("isso/(?!lib)", 10)))
 
-    app = ProxyFix(
-            wsgi.SubURI(
-                wsgi.CORSMiddleware(
-                    SharedDataMiddleware(
-                        ProfilerMiddleware(
-                            local_manager.make_middleware(isso)), {
-                        '/js': join(dirname(__file__), 'js/'),
-                        '/css': join(dirname(__file__), 'css/')}),
-                    origin(isso.conf.getiter("general", "host")))))
+    wrapper.append(partial(SharedDataMiddleware, exports={
+        '/js': join(dirname(__file__), 'js/'),
+        '/css': join(dirname(__file__), 'css/')}))
 
-    return app
+    wrapper.append(partial(wsgi.CORSMiddleware,
+        origin=origin(isso.conf.getiter("general", "host"))))
+
+    wrapper.extend([wsgi.SubURI, ProxyFix])
+
+    return reduce(lambda x, f: f(x), wrapper, isso)
 
 
 def main():
@@ -221,9 +224,5 @@ def main():
                 raise
         wsgi.SocketHTTPServer(sock, make_app(conf)).serve_forever()
 
-try:
-    import uwsgi
-except ImportError:
-    pass
-else:
-    application = make_app(Config.load(os.environ.get('ISSO_SETTINGS')))
+
+application = make_app(Config.load(os.environ.get('ISSO_SETTINGS')))
diff --git a/isso/core.py b/isso/core.py
index 645fcde..e030685 100644
--- a/isso/core.py
+++ b/isso/core.py
@@ -5,9 +5,10 @@ from __future__ import print_function
 import io
 import os
 import time
+import logging
 import binascii
 import threading
-import logging
+import multiprocessing
 
 from configparser import ConfigParser
 
@@ -213,6 +214,14 @@ class ThreadedMixin(Mixin):
             time.sleep(delta)
 
 
+class ProcessMixin(ThreadedMixin):
+
+    def __init__(self, conf):
+
+        super(ProcessMixin, self).__init__(conf)
+        self.lock = multiprocessing.Lock()
+
+
 class uWSGICache(object):
     """Uses uWSGI Caching Framework. INI configuration:
 
@@ -241,15 +250,7 @@ class uWSGIMixin(Mixin):
 
         super(uWSGIMixin, self).__init__(conf)
 
-        class Lock():
-
-            def __enter__(self):
-                uwsgi.lock()
-
-            def __exit__(self, exc_type, exc_val, exc_tb):
-                uwsgi.unlock()
-
-        self.lock = Lock()
+        self.lock = multiprocessing.Lock()
         self.cache = uWSGICache
 
         timedelta = conf.getint("moderation", "purge-after")