diff --git a/OpenCL/inc_vendor.h b/OpenCL/inc_vendor.h
index cbaf093f5..6ca2c5707 100644
--- a/OpenCL/inc_vendor.h
+++ b/OpenCL/inc_vendor.h
@@ -99,6 +99,11 @@
 #define REAL_SHM
 #endif
 
+// So far, only used by -m 22100 and only affects NVIDIA on OpenCL. CUDA seems to work fine.
+#ifdef FORCE_DISABLE_SHM
+#undef REAL_SHM
+#endif
+
 #ifdef REAL_SHM
 #define SHM_TYPE LOCAL_AS
 #else
diff --git a/src/modules/module_22100.c b/src/modules/module_22100.c
index 3c610f5c5..afbc29550 100644
--- a/src/modules/module_22100.c
+++ b/src/modules/module_22100.c
@@ -77,7 +77,7 @@ char *module_jit_build_options (MAYBE_UNUSED const hashconfig_t *hashconfig, MAY
   // NVIDIA GPU
   if (device_param->opencl_device_vendor_id == VENDOR_ID_NV)
   {
-    hc_asprintf (&jit_build_options, "-D _unroll");
+    hc_asprintf (&jit_build_options, "-D _unroll -D FORCE_DISABLE_SHM");
   }
 
   // AMD-GPU-PRO